Dr. Arun Jose (photo courtesy of University of Cincinnati College of Medicine)

K Scholar, Arun Jose, MD, MS, assistant professor in the Department of Internal Medicine, University of Cincinnati, recently published an article in Heart Failure Clinics titled, “Struggling between liver transplantation and portopulmonary hypertension”. To view the full article, please click here. 

Portopulmonary hypertension (PoPH) is a progressive, ultimately fatal cardiopulmonary disease that occurs exclusively in patients with underlying portal hypertensive liver disease. Although the mainstay of treatment in PoPH is targeted pulmonary vascular therapy, liver transplantation (LT) can be highly beneficial in select patients. This article, part of a featured issue on the challenges in pulmonary hypertension, reviews the rationale for medical therapy versus LT in PoPH, highlighting important clinical considerations and offering guidance to providers struggling to determine the optimal treatment approach for their PoPH patients.